D-Glucosamine Sulfate

What is D-Glucosamine Sulfate?

Molecular Formula (D-Glucosamine Sulfate): C₆H₁₅NO₉S

Molecular Weight: 277.25 g/mol

Chemical Name: 2-Amino-2-deoxy-D-Glucose Sulfate (Salt)

CAS Number: 29031-19-4

This compound is a substance naturally found in the cartilage within joints. It is commercially produced from the exoskeletons of crustaceans. It is also a sugar naturally found in the tissues and fluid surrounding our joints.

The most important factors enabling movement in the mobile parts of the human body are the joints. Joints facilitate movement; however, due to friction against each other, the fluid within them decreases over time, leading to osteoarthritis. This results in severe pain.

Other Names are as Follows;

• Glucosamine Sulfate
• Glucosamine
• D-Glucosamine Sulfate
• Sulfuric Acid-2-amino-2-deoxyhexose
• USP Grade
• Pharma Grade

How is D-Glucosamine Sulfate Produced?

D-Glucosamine Sulfate production is obtained from the shells of crustaceans.

Another method for production is using suitable plants in an environment with a hydroponic culture system. The plant used can be from the Cichorium, Daucus, Beta, and Helianthus species. Or these plant species can be used in combination.

First, the area where these plants will be grown is supported with nitrogen-containing fertilizers. The purpose is to ensure the formation of the Glucosamine Sulfate precursor in the plant. The fertilizer used consists of ammonium salts.

The reason for using nitrogen-containing fertilizer is that it has been determined to increase glucosamine formation in the plant by an additional 5 g per 5 kg.

The produced plants are heated in water between 70 °C and 110 °C for more than 1 hour. It is then extracted and dried.

What are the Physical and Chemical Properties?

Physically, it has an off-white powder form.

Melting point is 116 °C.

Density: 0.8 – 1.0 g/cm³

Boiling Point: No information available.

In terms of solubility, it has a solubility of 1 mg in 1 mL of 1M Hydrochloric Acid.

What are the Usage Areas of D-Glucosamine Sulfate?

• Osteoarthritis occurs as a result of excessive joint movement and cartilage deformation in the body. This results in severe joint pain. To alleviate such ailments, the cartilage needs to regenerate itself. In such cases, supplements containing D-Glucosamine Sulfate, which provides cartilage repair, are produced to relieve joint pain. It is the most important component in supplements produced to relieve joint pain and treat the disease.
• Supplements containing glucosamine for the treatment of inflammation causing osteoarthritis also make a significant contribution to treating damaged joints in the body.
• It has been determined that people experiencing joint pain have a sulfur deficiency. In arthritis patients, if sulfur is deficient, enzymes that cause cartilage destruction work more effectively, and arthritis occurs.
• Glucosamine prevents the skin from scaling. It prevents it from taking a dry form and has the ability to heal the skin. Therefore, it is used in the manufacture of beauty creams by being modified with hyaluronic acid.
• For treating joint and muscle pain, Glucosamine Sulfate is used in complex gel production. In this application, it is modified with menthol, triethanolamine (TEA), Carbomer, and some herbal extracts.
• It is a chemical with anti-aging properties for the skin.

What are the Factors Affecting Prices?

The price of D-Glucosamine Sulfate is directly dependent on the prices of the plants used in its production. Especially as white chicory plant prices increase, glucosamine prices will increase.

In the last 10 years, the price of this chemical compound has risen with the increase in the usage amount of D-Glucosamine Sulfate in the medical field. Prices have significantly increased due to difficulties in production and costs in the extraction process.

The D-Glucosamine Sulfate distributor keeps the sales of this compound under control. Prices rise with the increase in demand.